How does re-classification of variants of unknown significance (VUS) impact the management of patients at risk for hereditary breast cancer?

How does re-classification of variants of unknown significance (VUS) impact the management of patients at risk for hereditary breast cancer?

Abstract Background The popularity of multigene testing increases the probability of identifying variants of uncertain significance (VUS). While accurate variant interpretation enables clinicians to be better informed of the genetic risk of their patients, currently, there is a lack of consensus man...

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Main Authors: Ava Kwong (Author), Cecilia Yuen Sze Ho (Author), Vivian Yvonne Shin (Author), Chun Hang Au (Author), Tsun-Leung Chan (Author), Edmond Shiu Kwan Ma (Author)
Format: Book
Published: BMC, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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