Shared etiology of Mendelian and complex disease supports drug discovery

Abstract Background Drugs targeting disease causal genes are more likely to succeed for that disease. However, complex disease causal genes are not always clear. In contrast, Mendelian disease causal genes are well-known and druggable. Here, we seek an approach to exploit the well characterized biol...

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Main Authors: Panagiotis N. Lalagkas (Author), Rachel D. Melamed (Author)
Format: Book
Published: BMC, 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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