Calcitriol Reverses Induced Expression of Efflux Proteins and Potentiates Cytotoxic Activity of Gemcitabine in Capan-2 Pancreatic Cancer Cells

• मुख्य लेखकों: Hamed Gilzad-Kohan (लेखक), Shabnam Sani (लेखक), Mehdi Boroujerdi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Purpose. Efflux and influx proteins play a major role in chemo-resistance by affecting the net cellular uptake of anti-cancer drugs. Hence, alteration of the efflux and influx protein expression may result in variations of chemotherapeutics uptake and consequently cell death rate. The present study...