Intranasal Delivery of Cell-Penetrating Therapeutic Peptide Enhances Brain Delivery, Reduces Inflammation, and Improves Neurologic Function in Moderate Traumatic Brain Injury

• Main Authors: Yaswanthi Yanamadala (Author), Ritika Roy (Author), Afrika Alake Williams (Author), Navya Uppu (Author), Audrey Yoonsun Kim (Author), Mark A. DeCoster (Author), Paul Kim (Author), Teresa Ann Murray (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Following traumatic brain injury (TBI), secondary brain damage due to chronic inflammation is the most predominant cause of the delayed onset of mood and memory disorders. Currently no therapeutic approach is available to effectively mitigate secondary brain injury after TBI. One reason is the blood...