Altered composition and functional profile of high-density lipoprotein in leprosy patients.

• Main Authors: Robertha Mariana R Lemes (Author), Carlos Adriano de M E Silva (Author), Maria Ângela de M Marques (Author), Georgia C Atella (Author), José Augusto da C Nery (Author), Maria Renata S Nogueira (Author), Patricia S Rosa (Author), Cléverson T Soares (Author), Prithwiraj De (Author), Delphi Chatterjee (Author), Maria Cristina V Pessolani (Author), Cristiana S de Macedo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The changes in host lipid metabolism during leprosy have been correlated to fatty acid alterations in serum and with high-density lipoprotein (HDL) dysfunctionality. This is most evident in multibacillary leprosy patients (Mb), who present an accumulation of host lipids in Schwann cells and macropha...