Evaluating efficacy and safety of sub-anesthetic dose esketamine as an adjuvant to propofol/remifentanil analgosedation and spontaneous respiration for children flexible fibreoptic bronchoscopy: a prospective, double-blinded, randomized, and placebo-controlled clinical trial

• Главные авторы: Yu Zhong (Автор), Min Jiang (Автор), Yunshi Wang (Автор), Tingting Su (Автор), Yuanzhi Lv (Автор), Zhiqing Fan (Автор), Hengyi Ning (Автор), Yilan Yang (Автор), Yanhua Chen (Автор), Yubo Xie (Автор)
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• Опубликовано: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Предметы: article
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Background: Flexible fiberoptic bronchoscopy (FFB) for children is widely performed under sedation. Currently, the optimal sedation regimen remains unclear. Esketamine is an N-methyl-D-aspartic acid (NMDA) receptor antagonist, which has stronger sedative and analgesic effects and exerts less cardior...