Transient multifocal genomic crisis creating chromothriptic and non-chromothriptic rearrangements in prezygotic testicular germ cells

• Үндсэн зохиолчид: Atsushi Hattori (Зохиогч), Kohji Okamura (Зохиогч), Yumiko Terada (Зохиогч), Rika Tanaka (Зохиогч), Yuko Katoh-Fukui (Зохиогч), Yoichi Matsubara (Зохиогч), Keiko Matsubara (Зохиогч), Masayo Kagami (Зохиогч), Reiko Horikawa (Зохиогч), Maki Fukami (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2019-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background The co-occurrence of multiple de novo copy number variations (CNVs) is a rare phenomenon in the human genome. Recently, an "organismal CNV mutator phenotype" has been reported to result in transient genomic instability introducing multiple de novo CNVs in primary oocyte...