Transient multifocal genomic crisis creating chromothriptic and non-chromothriptic rearrangements in prezygotic testicular germ cells

• Main Authors: Atsushi Hattori (Author), Kohji Okamura (Author), Yumiko Terada (Author), Rika Tanaka (Author), Yuko Katoh-Fukui (Author), Yoichi Matsubara (Author), Keiko Matsubara (Author), Masayo Kagami (Author), Reiko Horikawa (Author), Maki Fukami (Author)
• Format: Book
• Published: BMC, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The co-occurrence of multiple de novo copy number variations (CNVs) is a rare phenomenon in the human genome. Recently, an "organismal CNV mutator phenotype" has been reported to result in transient genomic instability introducing multiple de novo CNVs in primary oocyte...