Potential for treatment benefit of STING agonists plus immune checkpoint inhibitors in oral squamous cell carcinoma
Abstract Background DNA-sensing receptor cyclic GMP-AMP synthase (cGAS) and its downstream signaling effector stimulator of interferon genes (STING) present a novel role in anti-tumor immunity. Recently, the combination of cGAS-STING agonists and immunotherapy achieved promising results in some tumo...
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2021-10-01T00:00:00Z.
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