Concepts and Challenges of Biosimilars in Breast Cancer: The Emergence of Trastuzumab Biosimilars

• Glavni autori: Alina Uifălean (Autor), Maria Ilieş (Autor), Raul Nicoară (Autor), Lucia Maria Rus (Autor), Simona Codruţa Hegheş (Autor), Cristina-Adela Iuga (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2018-09-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

With the development of anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibodies, trastuzumab-based therapy has become the standard of care among patients with early or advanced HER2-positive breast cancer. However, real-world data have shown that up to a half of patients do not re...