Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario

• Main Authors: Piyali Majumder (Author), Kasturi Roy (Author), Brijesh Kumar Singh (Author), Nihar Ranjan Jana (Author), Debashis Mukhopadhyay (Author)
• Format: Book
• Published: The Company of Biologists, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) manifests as neuronal loss. On the premise of Grb2 overexpression in AD mouse brain and brain tissues of AD patients, our study primarily focuses on the stability of cytoskeletal proteins in the context of degenerative AD-like conditions. Two predominant molecular featu...