Enhancing Patient Selection in Sepsis Clinical Trials Design Through an AI Enrichment Strategy: Algorithm Development and Validation

• Ngā kaituhi matua: Meicheng Yang (Author), Jinqiang Zhuang (Author), Wenhan Hu (Author), Jianqing Li (Author), Yu Wang (Author), Zhongheng Zhang (Author), Chengyu Liu (Author), Hui Chen (Author)
• Hōputu: Pukapuka
• I whakaputaina: JMIR Publications, 2024-09-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

BackgroundSepsis is a heterogeneous syndrome, and enrollment of more homogeneous patients is essential to improve the efficiency of clinical trials. Artificial intelligence (AI) has facilitated the identification of homogeneous subgroups, but how to estimate the uncertainty of the model outputs when...