Kynureninase Promotes Immunosuppression and Predicts Survival in Glioma Patients: In Silico Data Analyses of the Chinese Glioma Genome Atlas (CGGA) and of the Cancer Genome Atlas (TCGA)

• Автори: Gonzalo Pérez de la Cruz (Автор), Verónica Pérez de la Cruz (Автор), Javier Navarro Cossio (Автор), Gustavo Ignacio Vázquez Cervantes (Автор), Aleli Salazar (Автор), Mario Orozco Morales (Автор), Benjamin Pineda (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-02-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Kynureninase (KYNU) is a kynurenine pathway (KP) enzyme that produces metabolites with immunomodulatory properties. In recent years, overactivation of KP has been associated with poor prognosis of several types of cancer, in particular by promoting the invasion, metastasis, and chemoresistance of ca...