VPS38/UVRAG and ATG14, the variant regulatory subunits of the ATG6/Beclin1-PI3K complexes, are crucial for the biogenesis of the yolk organelles and are transcriptionally regulated in the oocytes of the vector Rhodnius prolixus.

• Hoofdauteurs: Priscila H Vieira (Auteur), Claudia F Benjamim (Auteur), Georgia Atella (Auteur), Isabela Ramos (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2021-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

In insects the reserve proteins are stored in the oocytes into endocytic-originated vesicles named yolk organelles. VPS38/UVRAG and ATG14 are the variant regulatory subunits of two class-III ATG6/Beclin1 PI3K complexes that regulate the recruitment of the endocytic (complex II) and autophagic (compl...