Exogenous insulin‐like growth factor 1 attenuates cisplatin‐induced muscle atrophy in mice

• Main Authors: Hiroyasu Sakai (Author), Maho Asami (Author), Hiroaki Naito (Author), Satoko Kitora (Author), Yuta Suzuki (Author), Yu Miyauchi (Author), Rei Tachinooka (Author), Satoshi Yoshida (Author), Risako Kon (Author), Nobutomo Ikarashi (Author), Yoshihiko Chiba (Author), Junzo Kamei (Author)
• Format: Book
• Published: Wiley, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A reduction in the skeletal muscle mass worsens the prognosis of patients with various cancers. Our previous studies indicated that cisplatin administration to mice caused muscle atrophy. This is a concern for human patients receiving cisplatin. The insulin‐like growth factor 1 (...