Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis

• Main Authors: Lingxiao Xu (Author), Qiuyue Peng (Author), Wenhua Xuan (Author), Xiaoke Feng (Author), Xiangqing Kong (Author), Miaojia Zhang (Author), Wenfeng Tan (Author), Meilang Xue (Author), Fang Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have recently shown that IL-29 was an important proinflammatory cytokine in pathogenesis of rheumatoid arthritis (RA). Inflammation also contributes to the pathogenesis of osteoarthritis (OA). The aim of this study was to investigate the effect and mechanism of IL-29 on cytokine production and ca...