Identification of lysyl oxidase as an adipocyte-secreted mediator that promotes a partial mesenchymal-to-epithelial transition in MDA-MB-231 cells

• Main Authors: Cassidy M. Van Stiphout (Author), Grant Kelly (Author), Nikitha K. Pallegar (Author), Eman Elbakry (Author), Ana Valeria Vilchis-Celis (Author), Sherri L. Christian (Author), Alicia M. Viloria-Petit (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Breast cancer (BC) is the most common cancer in women worldwide, where adiposity has been linked to BC morbidity. In general, obese premenopausal women diagnosed with triple-negative BC (TNBC) tend to have larger tumours with more metastases, particularly to the bone marrow, and worse prognosis...