Protandim Protects Oligodendrocytes against an Oxidative Insult

• Main Authors: Jamie L. Lim (Author), Susanne M. A. van der Pol (Author), Wia Baron (Author), Joe M. McCord (Author), Helga E. de Vries (Author), Jack van Horssen (Author)
• Format: Book
• Published: MDPI AG, 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oligodendrocyte damage and loss are key features of multiple sclerosis (MS) pathology. Oligodendrocytes appear to be particularly vulnerable to reactive oxygen species (ROS) and cytokines, such as tumor necrosis factor-α (TNF), which induce cell death and prevent the differentiation of oligodendrocy...