T cell-depleted hla-haploidentical stem cell transplantation in thalassemia young patients
The cure for thalassemia involves correcting the genetic defect in a hematopoietic stem cell that results in reduced or absent β-globin synthesis and an excess of α-globin dimers. Intracellular precipitation and accumulation of α- dimers results in ineffective erythropoiesis and hemolytic anemia. Re...
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MDPI AG,
2011-06-01T00:00:00Z.
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