T cell-depleted hla-haploidentical stem cell transplantation in thalassemia young patients

The cure for thalassemia involves correcting the genetic defect in a hematopoietic stem cell that results in reduced or absent β-globin synthesis and an excess of α-globin dimers. Intracellular precipitation and accumulation of α- dimers results in ineffective erythropoiesis and hemolytic anemia. Re...

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Main Authors: Pietro Sodani (Author), Antonella Isgrò (Author), Javid Gaziev (Author), Katia Paciaroni (Author), Marco Marziali (Author), Maria Domenica Simone (Author), Andrea Roveda (Author), Gioa De Angelis (Author), Cristiano Gallucci (Author), Fabio Torelli (Author), Giancarlo Isacchi (Author), Francesco Zinno (Author), Fabiola Landi (Author), Gaspare Adorno (Author), Alessandro Lanti (Author), Manuela Testi (Author), Marco Andreani (Author), Guido Lucarelli (Author)
Formato: Livro
Publicado em: MDPI AG, 2011-06-01T00:00:00Z.
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3rd Floor Main Library

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