Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors

• Main Authors: Sonja Oehmcke-Hecht (Author), Claudia Maletzki (Author), Surabhi Surabhi (Author), Nikolai Siemens (Author), Valeria Khaimov (Author), Lisa Marie John (Author), Sina Mariella Peter (Author), Sven Hammerschmidt (Author), Bernd Kreikemeyer (Author)
• Format: Book
• Published: Karger Publishers, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The coagulation and contact systems are parts of the innate immune system as they prevent bleeding and dissemination of pathogens and also contribute to microbial killing by inflammatory reactions and the release of antimicrobial peptides. Here, we investigated the influence of Streptococcus pneumon...