Juvenile idiopathic arthritis polygenic risk scores are associated with cardiovascular phenotypes in early adulthood: a phenome-wide association study

• Main Authors: Sarah L. N. Clarke (Author), Hannah J. Jones (Author), Gemma C. Sharp (Author), Kayleigh E. Easey (Author), Alun D. Hughes (Author), Athimalaipet V. Ramanan (Author), Caroline L. Relton (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background There is growing concern about the long-term cardiovascular health of patients with juvenile idiopathic arthritis (JIA). In this study we assessed the association between JIA polygenic risk and cardiovascular phenotypes (cardiovascular risk factors, early atherosclerosis/arterios...