Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors

• Main Authors: Yan Chen (Author), Xingguo Hou (Author), Dapeng Li (Author), Jin Ding (Author), Jiayue Liu (Author), Zilei Wang (Author), Fei Teng (Author), Hongjun Li (Author), Fan Zhang (Author), Yi Gu (Author), Steven Yu (Author), Xueming Qian (Author), Zhi Yang (Author), Hua Zhu (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Claudin18.2 (CLDN18.2) is a tight junction protein that is overexpressed in a variety of solid tumors such as gastrointestinal cancer and oesophageal cancer. It has been identified as a promising target and a potential biomarker to diagnose tumor, evaluate efficacy, and determine patient prognosis....