Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors

Oxidative stress is one of the main causes of significant severe diseases. The discovery of new potent antioxidants with high efficiency and low toxicity is a great demand in the field of medicinal chemistry. Herein, we report the design, synthesis molecular modelling and biological evaluation of no...

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Main Authors: Sahar A. Ali (Author), Samir Mohamed Awad (Author), Ahmed Mohammed Said (Author), Shahenda Mahgoub (Author), Heba Taha (Author), Naglaa Mohamed Ahmed (Author)
Formato: Livro
Publicado em: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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