Association of MTHFD1 gene polymorphisms and maternal smoking with risk of congenital heart disease: a hospital-based case-control study

• Автори: Xinli Song (Автор), Qiongxuan Li (Автор), Jingyi Diao (Автор), Jinqi Li (Автор), Yihuan Li (Автор), Senmao Zhang (Автор), Lijuan Zhao (Автор), Letao Chen (Автор), Jianhui Wei (Автор), Jing Shu (Автор), Yiping Liu (Автор), Mengting Sun (Автор), Peng Huang (Автор), Tingting Wang (Автор), Jiabi Qin (Автор)
• Формат: Книга
• Опубліковано: BMC, 2022-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background MTHFD1 gene may affect the embryonic development by elevated homocysteine levels, DNA synthesis and DNA methylation, but limited number of genetic variants of MTHFD1 gene was focused on the association with congenital heart disease (CHD). This study examined the role of MTHFD1 ge...