Study of Iron Piperazine-Based Chelators as Potential Siderophore Mimetics

• Main Authors: Pauline Loupias (Author), Isabelle Dechamps-Olivier (Author), Laurent Dupont (Author), Pierre Vanlemmens (Author), Catherine Mullié (Author), Nicolas Taudon (Author), Anne Bouchut (Author), Alexandra Dassonville-Klimpt (Author), Pascal Sonnet (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2019-10-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Gram-negative bacteria’s resistance such as <i>Pseudomonas aeruginosa</i> and the <i>Burkholderia</i> group to conventional antibiotics leads to therapeutic failure. Use of siderophores as Trojan horses to internalize antibacterial agents or toxic metals within bacteria is a...