Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-19

• Main Authors: Takahiro Kawasaki (Author), Yoshito Takeda (Author), Ryuya Edahiro (Author), Yuya Shirai (Author), Mari Nogami-Itoh (Author), Takanori Matsuki (Author), Hiroshi Kida (Author), Takatoshi Enomoto (Author), Reina Hara (Author), Yoshimi Noda (Author), Yuichi Adachi (Author), Takayuki Niitsu (Author), Saori Amiya (Author), Yuta Yamaguchi (Author), Teruaki Murakami (Author), Yasuhiro Kato (Author), Takayoshi Morita (Author), Hanako Yoshimura (Author), Makoto Yamamoto (Author), Daisuke Nakatsubo (Author), Kotaro Miyake (Author), Takayuki Shiroyama (Author), Haruhiko Hirata (Author), Jun Adachi (Author), Yukinori Okada (Author), Atsushi Kumanogoh (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The coronavirus disease 2019 (COVID-19) pandemic is widespread; however, accurate predictors of refractory cases have not yet been established. Circulating extracellular vesicles, involved in many pathological processes, are ideal resources for biomarker exploration. Methods To i...