Carbocisteine Improves Histone Deacetylase 2 Deacetylation Activity via Regulating Sumoylation of Histone Deacetylase 2 in Human Tracheobronchial Epithelial Cells

• Autori principali: Yun Song (Autore), Dan-Yi Chi (Autore), Ping Yu (Autore), Juan-Juan Lu (Autore), Jian-Rong Xu (Autore), Pan-Pan Tan (Autore), Bin Wang (Autore), Yong-Yao Cui (Autore), Hong-Zhuan Chen (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Histone deacetylase (HDAC) 2 plays a vital role in modifying histones to mediate inflammatory responses, while HDAC2 itself is commonly regulated by post-translational modifications. Small ubiquitin-related modifier (SUMO), as an important PTM factor, is involved in the regulation of multiple protei...