Bone formation with functionalized 3D printed poly-ε-caprolactone scaffold with plasma-rich-fibrin implanted in critical-sized calvaria defect of rat

• Main Authors: Min-Chia Chen (Author), Hsien-Chung Chiu (Author), Po-Jan Kuo (Author), Cheng-Yang Chiang (Author), Martin M. Fu (Author), Earl Fu (Author)
• Format: Book
• Published: Elsevier, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Space-making is one of the essential factors for bone regeneration in severe bony defect. To test the hypothesis that an appropriately designed scaffold may be beneficial for the bone formation in defect, the new bone formed in the critical-size calvarial defect of rat was examin...