HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer

• Main Authors: Feng-Jiao Wang (Author), Yan-Hua Jing (Author), Chien-Shan Cheng (Author), Zhang-Qi Cao (Author), Ju-Ying Jiao (Author), Zhen Chen (Author)
• Format: Book
• Published: BMC, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background SMARCAs, belonged to SWI/SNF2 subfamilies, are critical to cellular processes due to their modulation of chromatin remodeling processes. Although SMARCAs are implicated in the tumor progression of various cancer types, our understanding of how those members affect pancreatic carc...