HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer

• Главные авторы: Feng-Jiao Wang (Автор), Yan-Hua Jing (Автор), Chien-Shan Cheng (Автор), Zhang-Qi Cao (Автор), Ju-Ying Jiao (Автор), Zhen Chen (Автор)
• Формат: ‌
• Опубликовано: BMC, 2021-07-01T00:00:00Z.
• Предметы: article
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Abstract Background SMARCAs, belonged to SWI/SNF2 subfamilies, are critical to cellular processes due to their modulation of chromatin remodeling processes. Although SMARCAs are implicated in the tumor progression of various cancer types, our understanding of how those members affect pancreatic carc...