MALAT1 Mediates α-Synuclein Expression through miR-23b-3p to Induce Autophagic Impairment and the Inflammatory Response in Microglia to Promote Apoptosis in Dopaminergic Neuronal Cells

• Автори: Xin Geng (Автор), Yanghong Zou (Автор), Shipeng Li (Автор), Renli Qi (Автор), Hualin Yu (Автор), Jinghui Li (Автор)
• Формат: Книга
• Опубліковано: Hindawi Limited, 2023-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background. Parkinson's disease (PD) is a very common neurodegenerative disease that adversely affects the physical and mental health of many patients, but there is currently no effective treatment. Objective. To this end, this study focused on investigating the potential mechanisms leading to...