18F-labeled tracers targeting fibroblast activation protein

• Main Authors: Thomas Lindner (Author), Annette Altmann (Author), Frederik Giesel (Author), Clemens Kratochwil (Author), Christian Kleist (Author), Susanne Krämer (Author), Walter Mier (Author), Jens Cardinale (Author), Hans-Ulrich Kauczor (Author), Dirk Jäger (Author), Jürgen Debus (Author), Uwe Haberkorn (Author)
• Format: Book
• Published: SpringerOpen, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer-associated fibroblasts are found in the stroma of epithelial tumors. They are characterized by overexpression of the fibroblast activation protein (FAP), a serine protease which was already proven as attractive target for chelator-based theranostics. Unfortunately, the val...