A mouse model of neoadjuvant chemotherapy followed by interval cytoreductive surgery indicates impaired efficacy of perioperative cisplatin

• Main Authors: Mitchell Clark (Author), Alexandra Kollara (Author), Theodore J. Brown (Author), Taymaa May (Author)
• Format: Bog
• Udgivet: BMC, 2021-11-01T00:00:00Z.
• Fag: article
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Abstract Background Investigate the impact of interval cytoreductive surgery (ICS) on progression in an orthotopic mouse model of ovarian cancer and the impact of chemotherapy delivered at various timelines following surgery. Methods Luciferase-expressing ID8 murine ovarian cancer cells were implant...