Dry Powder Comprised of Isoniazid-Loaded Nanoparticles of Hyaluronic Acid in Conjugation with Mannose-Anchored Chitosan for Macrophage-Targeted Pulmonary Administration in Tuberculosis

Dry Powder Comprised of Isoniazid-Loaded Nanoparticles of Hyaluronic Acid in Conjugation with Mannose-Anchored Chitosan for Macrophage-Targeted Pulmonary Administration in Tuberculosis

Marketed dosage forms fail to deliver anti-tubercular drugs directly to the lungs in pulmonary Tuberculosis (TB). Therefore, nanomediated isoniazid (INH)-loaded dry powder for inhalation (Nano-DPI) was developed for macrophage-targeted delivery in TB. Mannosylated chitosan (MC) and hyaluronic acid (...

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Main Authors: Mahwash Mukhtar (Author), Noemi Csaba (Author), Sandra Robla (Author), Rubén Varela-Calviño (Author), Attila Nagy (Author), Katalin Burian (Author), Dávid Kókai (Author), Rita Ambrus (Author)
Format: Book
Published: MDPI AG, 2022-07-01T00:00:00Z.
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