Soft TCPTP agonism - Novel target to rescue airway epithelial integrity by exogenous spermidine

• Main Authors: Carlo eGhisalberti (Author), Rosa Maria eBorzì (Author), Silvia eCetrullo (Author), Flavio eFlamigni (Author), Gaetano eCairo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A reparative approach of disrupted epithelium in obstructive airway diseases, namely asthma and chronic obstructive pulmonary disease (COPD), may afford protection and long-lasting results compared to conventional therapies, e.g. corticosteroids or immunosuppressant drugs. Here we propose the polyam...