Optimal LDR to Protect the Kidney From Diabetes: Whole-Body Exposure to 25 mGy X-rays Weekly for 8 Weeks Efficiently Attenuates Renal Damage in Diabetic Mice

• Main Authors: Jie Cheng (Author), Fengsheng Li (Author), Guanjun Wang (Author), Weiying Guo (Author), Shan Huang (Author), Brian Wang (Author), Cai Li (Author), Qisheng Jiang (Author), Lu Cai (Author), Jiuwei Cui (Author)
• Format: Book
• Published: SAGE Publishing, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To explore an optimal frequency of whole-body low-dose radiation (LDR) to protect the kidney from diabetes, type 1 diabetic mice were induced with multiple injections of low-dose streptozotocin in male C57BL/6J mice. Diabetic or age-matched normal mice received whole-body exposure to 12.5 or 25 mGy...