Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjӧgren's syndrome

• Main Authors: Jimin Yoon (Author), Minseok Lee (Author), Ahsan Ausaf Ali (Author), Ye Rim Oh (Author), Yong Seok Choi (Author), Sujin Kim (Author), Namseok Lee (Author), Se Gwang Jang (Author), Seonghyeon Park (Author), Jin-Haeng Chung (Author), Seung-Ki Kwok (Author), Joon Young Hyon (Author), Seunghee Cha (Author), Yun Jong Lee (Author), Sung Gap Im (Author), Yoosik Kim (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sjӧgren's syndrome (SS) is a systemic autoimmune disease that targets the exocrine glands, resulting in impaired saliva and tear secretion. To date, type I interferons (I-IFNs) are increasingly recognized as pivotal mediators in SS, but their endogenous drivers have not been elucidated. Here, w...