Piezo1 activation facilitates ovarian cancer metastasis via Hippo/YAP signaling axis

• Main Authors: Yanjie Xiong (Author), Liru Dong (Author), Yun Bai (Author), Hui Tang (Author), Shuang Li (Author), Dan Luo (Author), Fang Liu (Author), Jie Bai (Author), Shikun Yang (Author), Xudong Song (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ovarian cancer (OC) is a highly malignant cancer with great metastatic potential. Here we aimed to investigate the role of Piezo1, a gene related to the mechanical environment of the tumor, in promoting the metastasis of OC. We performed Piezo1 knockdown in A-1847 cells using small hairpin RNAs, and...