Piezo1 activation facilitates ovarian cancer metastasis via Hippo/YAP signaling axis

• Egile Nagusiak: Yanjie Xiong (Egilea), Liru Dong (Egilea), Yun Bai (Egilea), Hui Tang (Egilea), Shuang Li (Egilea), Dan Luo (Egilea), Fang Liu (Egilea), Jie Bai (Egilea), Shikun Yang (Egilea), Xudong Song (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Ovarian cancer (OC) is a highly malignant cancer with great metastatic potential. Here we aimed to investigate the role of Piezo1, a gene related to the mechanical environment of the tumor, in promoting the metastasis of OC. We performed Piezo1 knockdown in A-1847 cells using small hairpin RNAs, and...