The role of 5-HTergic neuron activation in the rapid antidepressant-like effects of hypidone hydrochloride (YL-0919) in mice

• Autori principali: Guang-Xiang Li (Autore), Jiao-Zhao Yan (Autore), Sun-Rui Sun (Autore), Xiao-Juan Hou (Autore), Yong-Yu Yin (Autore), Yun-Feng Li (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

IntroductionMajor depressive disorder (MDD) is a common and disabling mental health condition; the currently available treatments for MDD are insufficient to meet clinical needs due to their limited efficacy and slow onset of action. Hypidone hydrochloride (YL-0919) is a sigma-1 receptor agonist and...