Natural coumarins from Murraya paniculata as mixed-type inhibitors of cholinesterases: In vitro and in silico investigations

• Main Authors: Asaad Khalid (Author), Waqasuddin Khan (Author), Komal Zia (Author), Azizuddin (Author), Waquar Ahsan (Author), Hassan A. Alhazmi (Author), Ashraf N. Abdalla (Author), Asim Najmi (Author), Andleeb Khan (Author), Abdelhakim Bouyahya (Author), Zaheer Ul-Haq (Author), Ajmal Khan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Currently, acetylcholinesterase (AChE) inhibiting drugs in clinical use, such as tacrine, donepezil, rivastigmine, and galanthamine, are associated with serious side effects and short half-lives. In recent years, numerous phytochemicals have been identified as inhibitors of cholinesterases with pote...