Synthesis of a 2-nitroimidazole derivative N-(4-[18F]fluorobenzyl)-2-(2-nitro-1H-imidazol-1-yl)-acetamide ([18 F]FBNA) as PET radiotracer for imaging tumor hypoxia

• Main Authors: Arian Pérez Nario (Author), Jenilee Woodfield (Author), Sofia Nascimento dos Santos (Author), Cody Bergman (Author), Melinda Wuest (Author), Yasniel Babí Araújo (Author), André Luis Lapolli (Author), Frederick G. West (Author), Frank Wuest (Author), Emerson Soares Bernardes (Author)
• Format: Book
• Published: SpringerOpen, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Tissue hypoxia is a pathological condition characterized by reducing oxygen supply. Hypoxia is a hallmark of tumor environment and is commonly observed in many solid tumors. Non-invasive imaging techniques like positron emission tomography (PET) are at the forefront of detecting...