QBD approach for the development of hesperetin loaded colloidal nanosponges for sustained delivery: In-vitro, ex-vivo, and in-vivo assessment

• Main Authors: Kitty Rodrigues (Author), Sameer Nadaf (Author), Nilesh Rarokar (Author), Nilambari Gurav (Author), Pradnya Jagtap (Author), Prashant Mali (Author), Muniappan Ayyanar (Author), Mohan Kalaskar (Author), Shailendra Gurav (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hesperetin (HT) is a polyphenolic compound with anti-carcinogenic, tumor necrosis, and anti-oxidant properties. The present study reports the fabrication, optimization, and evaluation of HT-loaded nanosponges (HTN)- based gel (HTNG) for sustained anti-inflammatory effect. HTN formulation was prepare...