Preparation and evaluation of an oral mucoadhesive gel containing nystatin-loaded alginate microparticles

• Main Authors: Mohammadi Samani S. (Author), Karimaddini S. (Author), Sobhani Z. (Author), Ahmadi F. (Author)
• Format: Bog
• Udgivet: Sciendo, 2021-03-01T00:00:00Z.
• Fag: article
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Nystatin is an antifungal agent used for prophylaxis and treatment of candidiasis, especially oral mycosis. Efficacy of nystatin conventional dosage forms is limited by the short residence time and bitter taste of the drug. This research aims at designing an optimized formulation of oral mucoadhesiv...