Down Syndrome Due to Unbalanced Homologous Acrocentric Rearrangements and its Recurrence in Subsequent Pregnancies: Prenatal Diagnosis by Amniocentesis

• Main Authors: Chih-Ping Chen (Author), Schu-Rern Chern (Author), Fuu-Jen Tsai (Author), Pei-Chen Wu (Author), Shu-Shien Chiang (Author), Chen-Chi Lee (Author), Wayseen Wang (Author)
• Format: Book
• Published: Elsevier, 2009-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To present our experience of amniocentesis for the prenatal diagnosis of Down syndrome due to unbalanced homologous acrocentric rearrangements and its recurrence in subsequent pregnancies. Case Report: From January 1987 to September 2009, six cases with rea(21q21q) Down syndrome were diag...