On the kinetic features of orexin receptor antagonists at orexin receptors, transduction systems and receptor binding

• Main Authors: Daniel Hoyer (Author), Laura H. Jacobson (Author)
• Formato: Livro
• Publicado em: Elsevier, 2024-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Orexin receptor antagonists are on the market or under development for the treatment of insomnia and a number of other neuropsychiatric disorders. Currently, suvorexant, lemborexant and daridorexant, three dual orexin receptor antagonists (DORAs) have received market approval by regulatory authoriti...