RU.521 protects against neutrophil extracellular traps-induced vascular endothelial injury by inhibiting cGAS/STING pathway

• Main Authors: Biao Zhang (Author), Zaojun Fang (Author), Ying Lin (Author), Qian Wu (Author), Jiaping Chen (Author)
• 格式: 圖書
• 出版: Bangladesh Pharmacological Society, 2024-06-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

This study aims to investigate the effect of RU.521 on improving vascular endothelial injury in 14 acute lung injury patients. Serum myeloperoxidase, double-stranded DNA (dsDNA), IFN-β, and TNF-α levels of patients were detected by ELISA. Neutrophil extracellular traps were used to stimulate human v...