RU.521 protects against neutrophil extracellular traps-induced vascular endothelial injury by inhibiting cGAS/STING pathway

This study aims to investigate the effect of RU.521 on improving vascular endothelial injury in 14 acute lung injury patients. Serum myeloperoxidase, double-stranded DNA (dsDNA), IFN-β, and TNF-α levels of patients were detected by ELISA. Neutrophil extracellular traps were used to stimulate human v...

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Autores principales: Biao Zhang (Autor), Zaojun Fang (Autor), Ying Lin (Autor), Qian Wu (Autor), Jiaping Chen (Autor)
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Publicado: Bangladesh Pharmacological Society, 2024-06-01T00:00:00Z.
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