Long-Term Fenofibrate Treatment Stimulates the Phenotypic Microevolution of Prostate Cancer Cells In Vitro

• Autori principali: Karolina W. Warzecha (Autore), Maciej Pudełek (Autore), Jessica Catapano (Autore), Zbigniew Madeja (Autore), Jarosław Czyż (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Fenofibrate is a widely used anti-hyperlipidemic agonist of peroxisome proliferator-activated receptor alpha (PPARα). As a metabolic blocker, fenofibrate interferes with cancer promotion/progression via its misbalancing effects on cellular metabolism. However, the consequences of its long-term appli...