Transplacental Zika virus transmission in ex vivo perfused human placentas.

• Main Authors: Thomas Langerak (Author), Michelle Broekhuizen (Author), Peter-Paul Alexander Unger (Author), Lunbo Tan (Author), Marion Koopmans (Author), Eric van Gorp (Author), A H Jan Danser (Author), Barry Rockx (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A Zika virus (ZIKV) infection during pregnancy can result in severe birth defects such as microcephaly. To date, it is incompletely understood how ZIKV can cross the human placenta. Furthermore, results from studies in pregnant mice and non-human primates are conflicting regarding the role of cross-...