Discovery and development of natural heat shock protein 90 inhibitors in cancer treatment
Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone that plays a vital role in the signal transduction of cancers. Hsp90 inhibitors are able to inhibit Hsp90 or the complex of Hsp90 and co-chaperones resulting in the degradation of Hsp90-dependent client proteins through the ubiq...
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Main Authors: | Yong Li (Author), Dongmei Zhang (Author), Jun Xu (Author), Junmin Shi (Author), Lei Jiang (Author), Nan Yao (Author), Wencai Ye (Author) |
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Format: | Book |
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Elsevier,
2012-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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