Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study

• Main Authors: Michael M. Mendelson (Author), Roby Johannes (Author), Chunyu Liu (Author), Tianxiao Huan (Author), Chen Yao (Author), Xiao Miao (Author), Joanne M. Murabito (Author), Josée Dupuis (Author), Daniel Levy (Author), Emelia J. Benjamin (Author), Honghuang Lin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Transmembrane tumor necrosis factor (TNF) receptors are involved in inflammatory, apoptotic, and proliferative processes. In the bloodstream, soluble TNF receptor II (sTNFR2) can modify the inflammatory response of immune cells and is predictive of cardiovascular disease risk. We hypothe...