Mass spectrometry-based multi-attribute method in protein therapeutics product quality monitoring and quality control

• Main Authors: Feng Yang (Author), Jennifer Zhang (Author), Alexander Buettner (Author), Eva Vosika (Author), Monica Sadek (Author), Zhiqi Hao (Author), Dietmar Reusch (Author), Maximiliane Koenig (Author), Wayman Chan (Author), Anja Bathke (Author), Hilary Pallat (Author), Victor Lundin (Author), Jochen Felix Kepert (Author), Patrick Bulau (Author), Galahad Deperalta (Author), Christopher Yu (Author), Richard Beardsley (Author), Tura Camilli (Author), Reed Harris (Author), John Stults (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTThe multi-attribute method (MAM), a liquid chromatography-mass spectrometry (LC-MS)-based peptide mapping method, has gained increased interest and applications in the biopharmaceutical industry. MAM can, in one method, provide targeted quantitation of multiple site-specific product quality...